Photo of Sri-Rajasekhar (Raj) Kothapalli

Sri-Rajasekhar (Raj) Kothapalli

Associate Professor of Biomedical Engineering

Affiliation(s):

  • Biomedical Engineering
  • Center for Acoustics and Vibration
  • Acoustics

325 Chemical and Biomedical Engineering Building

szk416@psu.edu

814-865-0459

Personal or Departmental Website

Research Areas:

Medical Imaging

 
 

 

Education

  • M Phil, Condensed Matter Physics, University of Hyderabad, 1998
  • M.Eng, Applied Optics, I.I.T Delhi, 2000
  • MS, Applied Physics, University of Massachusetts, Boston, 2004
  • Ph D, Biomedical Engineering, Washington University in St. Louis, 2009
  • Postdoctoral, Radiology, Stanford University, 2013

Publications

Journal Articles

  • Chichen Huang and Sri-Rajasekhar Kothapalli, 2026, "Comprehensive parametric study of curved piezoelectric micromachined ultrasonic transducers.", Sensors and Actuators A: Physical, 410, (2)
  • Shubham Mirg, Krishnendu Samanta, Haoyang Chen, Jin Jiang, Kevin L. Turner, Fatemeh Salehi, Kathiravan M. Ramiah, Patrick Drew and Sri-Rajasekhar Kothapalli, 2026, "Integrated ultrasound stimulation and optical imaging of awake mice brain using a transparent ultrasound transducer cranial window", npj Acoustics, 2, (1)
  • Christopher Cheng and Sri-Rajasekhar Kothapalli, 2022, "Improving PMUT Receive Sensitivity via DC Bias and Piezoelectric Composition", Sensors, 22, (15)
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2022, "A Transparent Ultrasound Array for Real-Time Optical, Ultrasound, and Photoacoustic Imaging", AAAS BME Frontiers, 2022
  • Shubham Mirg and Sri-Rajasekhar Kothapalli, 2022, "Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window"
  • Sumit Agrawal, Thaarakh Suresh, Ankit Garikipati, Ajay Dangi and Sri-Rajasekhar Kothapalli, 2021, "Modeling combined ultrasound and photoacoustic imaging: Simulations aiding device development and artificial intelligence", Photoacoustics, 24, pp. 100304
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2021, "A High Sensitivity Transparent Ultrasound Transducer Based on PMN-PT for Ultrasound and Photoacoustic Imaging", IEEE Sensors Letters, 5, (11), pp. 1-4
  • Haoyang Chen and Sri-Rajasekhar Kothapalli, 2021, "A transparent low intensity pulsed ultrasound (LIPUS) chip for high-throughput cell stimulation", Lab on a Chip, 21, (24), pp. 4734-4742
  • Amirsaeed Yazdani and Sri-Rajasekhar Kothapalli, 2021, "Simultaneous Denoising and Localization Network for Photoacoustic Target Localization", IEEE Transactions on Medical Imaging, 40, (9), pp. 2367-2379
  • Ajay Dangi and Sri-Rajasekhar Kothapalli, 2019, "A Photoacoustic Imaging Device using Piezoelectric Micromachined Ultrasound Transducers (PMUTs)", IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

Research Projects

  • March 2023 - February 2028, "CAREER: Smart and scalable approaches for developing multimodal optical and acoustic imaging technologies," (Sponsor: National Science Foundation).
  • September 2023 - April 2027, "Clinical translation of dual-modality transrectal ultrasound and photoacoustic imaging for detection of aggressive prostate cancer," (Sponsor: National Cancer Institute).
  • May 2022 - March 2027, "Photoacoustic and epigenetic nerve scaffold for nerve regeneration," (Sponsor: National Institute of Neurological Disorders and Stroke).
  • August 2024 - July 2027, "Mechanisms of cognitive impairment caused by atherosclerosis and red blood cell released ATP," (Sponsor: National Institute of Neurological Disorders and Stroke).
  • September 2022 - August 2027, "Dual-modality Ultrasound and Photoacoustic Molecular Imaging Strategies for Lethal Prostate Cancer Detection," (Sponsor: Congressionally Directed Medical Research Programs).
  • September 2020 - August 2026, "A portable photoacoustic imager for diagnosing vascular diseases," (Sponsor: National Institute of Biomedical Imaging and Bioengineering).
  • September 2022 - August 2025, "Multiparametric Transrectal Ultrasound and Photoacoustic Imaging of Human Prostate," (Sponsor: National Institute of Biomedical Imaging and Bioengineering).
  • August 2021 - March 2025, "Collaborative Research: An implantable intracranial ultrasound stimulation for treating neurodiseases," (Sponsor: National Science Foundation).

Honors and Awards

  • NSF CAREER, National Science Foundation, March 2023 - February 2028
  • Best Paper Award, In Vivo Ultrasound Imaging GRC conference, August 2024 - August 2024
  • Best Paper Award Runner-Up, IEEE Sensors Letters, November 2022
  • NIH Pathway to Independence Grant Award K99/R00, National Institutes of Health, May 2014 - June 2021

Service

Service to Penn State:

  • Committee Work, Committee Member, Penn State University, Sustainability Council, August 2021

Service to External Organizations:

 


 

About

Founded in 1965, Penn State's Graduate Program in Acoustics has become the leading resource for graduate education in acoustics in the United States. The interdisciplinary program leads to the degrees: Master of Engineering in Acoustics (M.Eng.), Master of Science in Acoustics (M.S.), and Doctor of Philosophy in Acoustics (Ph.D.)

Graduate Program in Acoustics

College of Engineering

The Pennsylvania State University

14 Engineering Collaborative Research and Education Building

556 White Course Drive

University Park, PA 16802